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cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation

Inflammatory mediators like thrombin disrupt endothelial adherens junctions (AJs) and barrier integrity leading to oedema formation followed by resealing of AJs and a slow recovery of the barrier function. The molecular mechanisms of this process have not yet been fully delineated. The aim of the pr...

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Библиографические подробности
Опубликовано в: :Physiol Rep
Главные авторы: Aslam, Muhammad, Tanislav, Christian, Troidl, Christian, Schulz, Rainer, Hamm, Christian, Gündüz, Dursun
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley Periodicals, Inc. 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254100/
https://ncbi.nlm.nih.gov/pubmed/25344477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12175
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