Constitutive activation of the ERK pathway in melanoma and skin melanocytes in Grey horses

BACKGROUND: Constitutive activation of the ERK pathway, occurring in the vast majority of melanocytic neoplasms, has a pivotal role in melanoma development. Different mechanisms underlie this activation in different tumour settings. The Grey phenotype in horses, caused by a 4.6 kb duplication in int...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Jiang, Lin, Campagne, Cécile, Sundström, Elisabeth, Sousa, Pedro, Imran, Saima, Seltenhammer, Monika, Pielberg, Gerli, Olsson, Mats J, Egidy, Giorgia, Andersson, Leif, Golovko, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254013/
https://ncbi.nlm.nih.gov/pubmed/25413220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-857
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