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Immunogenicity and safety of Advax(™), a novel polysaccharide adjuvant based on delta inulin, when formulated with hepatitis B surface antigen; a randomized controlled Phase 1 study

There is a need for additional safe and effective human vaccine adjuvants. Advax is a novel adjuvant produced from semi-crystalline particles of delta inulin. In animal studies Advax enhanced humoral and cellular immunity to hepatitis B surface antigen (HBsAg) without inducing local or systemic reac...

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Опубликовано в: :Vaccine
Главные авторы: Gordon, David, Kelley, Peter, Heinzel, Susanne, Cooper, Peter, Petrovsky, Nikolai
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253909/
https://ncbi.nlm.nih.gov/pubmed/25267153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.09.034
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