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Linking 3D and 2D binding kinetics of membrane proteins by multiscale simulations

Membrane proteins are among the most functionally important proteins in cells. Unlike soluble proteins, they only possess two translational degrees of freedom on cell surfaces, and experience significant constraints on their rotations. As a result, it is currently challenging to characterize the in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Xie, Zhong-Ru, Chen, Jiawen, Wu, Yinghao
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253819/
https://ncbi.nlm.nih.gov/pubmed/25271078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2574
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