Hypoxic stress induces, but cannot sustain trophoblast stem cell differentiation to labyrinthine placenta due to mitochondrial insufficiency

Dysfunctional stem cell differentiation into placental lineages is associated with gestational diseases. Of the differentiated lineages available to trophoblast stem cells (TSC), elevated O(2) and mitochondrial function are necessary to placental lineages at the maternal-placental surface and import...

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Detalhes bibliográficos
Publicado no:Stem Cell Res
Main Authors: Xie, Yufen, Zhou, Sichang, Jiang, Zhongliang, Dai, Jing, Puscheck, Elizabeth E, Lee, Icksoo, Parker, Graham, Hüttemann, Maik, Rappolee, Daniel A
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253717/
https://ncbi.nlm.nih.gov/pubmed/25239494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2014.07.007
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