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The role of Intrahepatic CD3+/CD4−/CD8− double negative T (DN T) cells in enhanced acetaminophen toxicity

The role of the immune system, specifically NK, NKT and CD3 cells, in acetaminophen (APAP) induced liver injury remains inconsistently defined. In the present study, wild type (C57BL/6J) mice and granzyme B deficient (GrB −/−) mice were treated with acetaminophen to assess the role of the immune sys...

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Foilsithe in:Toxicol Appl Pharmacol
Main Authors: Getachew, Yonas, Cusimano, Frank A., James, Laura P., Thiele, Dwain L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253711/
https://ncbi.nlm.nih.gov/pubmed/25168425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2014.08.017
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