A randomized study on pharmacodynamic effects of vaginal rings delivering the progesterone receptor modulator, Ulipristal acetate. Research for a novel estrogen-free, method of contraception

OBJECTIVE: To determine whether a 3-month contraceptive vaginal ring (CVR) delivering ulipristal acetate (UPA) can inhibit ovulation in 90% of cycles. STUDY DESIGN: This was a randomized dose-finding parallel group clinical trial. Fifty-five healthy women with normal ovulation at baseline were rando...

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Publicat a:Contraception
Autors principals: Huang, YongMei, Jensen, Jeffrey T., Brache, Vivian, Cochon, Leila, Williams, Alistair, Miranda, Maria-José, Croxatto, Horacio, Kumar, Narender, Sussman, Heather, Hoskin, Elena, Plagianos, Marlena, Roberts, Kevin, Merkatz, Ruth, Blithe, Diana, Sitruk-Ware, Regine
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253673/
https://ncbi.nlm.nih.gov/pubmed/25193534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.contraception.2014.08.006
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