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Metformin protects against gentamicin-induced hair cell death in vitro but not ototoxicity in vivo

Metformin (N,N-dimethylbiguanidine) is a widely employed oral hypoglycemic agent for the management of type 2 diabetes mellitus. Its antioxidant properties and safe clinical use raise the possibility of preventing gentamicin-induced hearing loss in patients. Therefore, we screened the usefulness of...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Oishi, Naoki, Kendall, Ann, Schacht, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253637/
https://ncbi.nlm.nih.gov/pubmed/25240593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.09.028
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