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Gene structure, regulatory control, and evolution of black widow venom latrotoxins

Black widow venom contains α-latrotoxin, infamous for causing intense pain. Combining 33 kb of Latrodectus hesperus genomic DNA with RNA-Seq, we characterized the α-latrotoxin gene and discovered a paralog, 4.5 kb downstream. Both paralogs exhibit venom gland specific transcription, and may be regul...

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Détails bibliographiques
Publié dans:FEBS Lett
Auteurs principaux: Bhere, Kanaka Varun, Haney, Robert A., Ayoub, Nadia A., Garb, Jessica E.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253598/
https://ncbi.nlm.nih.gov/pubmed/25217831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.08.034
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