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Pharmacokinetics of Sustained-Release and Transdermal Buprenorphine in Göttingen Minipigs (Sus scrofa domestica)

The opioid buprenorphine has been shown to provide adequate postoperative analgesia in both companion and laboratory animals. However, its use is still hindered by the need for multiple parenteral injections to achieve continuous analgesia. The purpose of the current study was to conduct a pharmacok...

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Pubblicato in:J Am Assoc Lab Anim Sci
Autori principali: Thiede, Allison J, Garcia, Kelly D, Stolarik, DeAnne F, Ma, Junli, Jenkins, Gary J, Nunamaker, Elizabeth A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for Laboratory Animal Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253584/
https://ncbi.nlm.nih.gov/pubmed/25650977
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