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Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death
Mitochondrial fusion and fission is a dynamic process critical for the maintenance of mitochondrial function and cell viability. During excitotoxicity neuronal mitochondria are fragmented, but the mechanism underlying this process is poorly understood. Here, we show that Mfn2 is the only member of t...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253527/ https://ncbi.nlm.nih.gov/pubmed/25147362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488327 |
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