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The fatty acid synthase inhibitor triclosan: repurposing an anti-microbial agent for targeting prostate cancer

Inhibition of FASN has emerged as a promising therapeutic target in cancer, and numerous inhibitors have been investigated. However, severe pharmacological limitations have challenged their clinical testing. The synthetic FASN inhibitor triclosan, which was initially developed as a topical antibacte...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Sadowski, Martin C., Pouwer, Rebecca H., Gunter, Jennifer H., Lubik, Amy A., Quinn, Ronald J., Nelson, Colleen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253440/
https://ncbi.nlm.nih.gov/pubmed/25313139
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