Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab

Lung cancer, as well as lung metastases from distal primary tumors, could benefit from aerosol treatment. Unfortunately, because of lung physiology, clearance of nebulized drugs is fast, paralleled by unwanted systemic exposure. Here we report that nebulized AvidinOX can act as an artificial recepto...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Santis, Rita De, Rosi, Antonio, Anastasi, Anna Maria, Chiapparino, Caterina, Albertoni, Claudio, Leoni, Barbara, Pelliccia, Angela, Santapaola, Daniela, Carollo, Valeria, Marra, Emanuele, Aurisicchio, Luigi, Arseni, Brunilde, Pacello, Maria Lucrezia, Palmieri, Gabriella, Battella, Simone, Petronzelli, Fiorella, Milazzo, Ferdinando Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253431/
https://ncbi.nlm.nih.gov/pubmed/25238453
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