In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential

The oncogenic bHLH-LZ transcription factor Myc forms binary complexes with its binding partner Max. These and other bHLH-LZ-based protein-protein interactions (PPI) in the Myc-Max network are essential for the physiological and oncogenic activities of Myc. We have generated a genetically determined...

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Pubblicato in:Oncotarget
Autori principali: Raffeiner, Philipp, Röck, Ruth, Schraffl, Andrea, Hartl, Markus, Hart, Jonathan R., Janda, Kim D., Vogt, Peter K., Stefan, Eduard, Bister, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Priority Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253403/
https://ncbi.nlm.nih.gov/pubmed/25326649
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