Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells

BACKGROUND & AIMS: Cancer stem cells (CSCs) can contribute to hepatocellular carcinoma (HCC) progression and recurrence following therapy. The presence of tumor-associated macrophages (TAMs) in patients with HCC is associated with poor outcomes. It is not clear whether TAMs interact with CSCs du...

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Publicado no:Gastroenterology
Main Authors: Wan, Shanshan, Zhao, Ende, Kryczek, Ilona, Vatan, Linda, Sadovskaya, Anna, Ludema, Gregory, Simeone, Diane M., Zou, Weiping, Welling, Theodore H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253315/
https://ncbi.nlm.nih.gov/pubmed/25181692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.08.039
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