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Inherited incomplete deficiency of the fourth component of complement (C4) determined by a gene not linked to human histocompatibility leukocyte antigens.

We have studied a family in which the proband had systemic lupus erythematosus and selective incomplete deficiency of the fourth component of complement (C4) (2-5% of the normal level). An additional six healthy family members also had low C4 levels (2.4-24.1% of normal) but no evidence of lupus. Th...

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Udgivet i:J Clin Invest
Principais autores: Muir, W A, Hedrick, S, Alper, C A, Ratnoff, O D, Schacter, B, Wisnieski, J J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425321/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6480834/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111564
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