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Neurodevelopment and brain growth in classic Menkes disease is influenced by age and symptomatology at initiation of copper treatment

Menkes disease is an X-linked recessive disorder of brain copper metabolism caused by mutations in an essential mammalian copper transport gene, ATP7A. Untreated affected individuals suffer failure to thrive and neurodevelopmental delays that usually commence at 6 to 8 weeks of age. Death by age thr...

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Vydáno v:J Trace Elem Med Biol
Hlavní autor: Kaler, Stephen G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253077/
https://ncbi.nlm.nih.gov/pubmed/25281031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtemb.2014.08.008
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