Two rare AKAP9 variants are associated with Alzheimer disease in African Americans

BACKGROUND: Less is known about the genetic basis of Alzheimer disease (AD) in African Americans (AAs) than in non-Hispanic whites. METHODS: Whole exome sequencing (WES) was performed on seven AA AD cases. Disease association with potentially AD-related variants from WES was assessed in an AA discov...

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Udgivet i:Alzheimers Dement
Main Authors: Logue, Mark W., Schu, Matthew, Vardarajan, Badri N., Farrell, John, Bennett, David A., Buxbaum, Joseph D., Byrd, Goldie S., Ertekin-Taner, Nilufer, Evans, Denis, Foroud, Tatiana, Goate, Alison, Graff-Radford, Neill R., Kamboh, M. Ilyas, Kukull, Walter A., Manly, Jennifer J., Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Schellenberg, Gerard D., Lunetta, Kathryn L., Baldwin, Clinton T., Fallin, M. Daniele, Farrer, Lindsay A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253055/
https://ncbi.nlm.nih.gov/pubmed/25172201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2014.06.010
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