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Robust Expansion of Dendritic Cells in vivo by Hydrodynamic FLT3L-FC Gene Transfer
Due to low numbers of endogenous dendritic cells (DC) in vivo, exogenous DC-poietin Fms-like tyrosine kinase 3-ligand (FLT3L) is routinely used to generate DC for subsequent studies. We engineered a novel FLT3L-FC DNA construct that, when combined with hydrodynamic gene transfer (HDT), induced robus...
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| Publicado en: | J Immunol Methods |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253009/ https://ncbi.nlm.nih.gov/pubmed/25066631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.07.008 |
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