Overexpression of Toll-like receptor 8 correlates with the progression of podocyte injury in murine autoimmune glomerulonephritis

Members of the Toll-like receptor (TLR) family serve as pathogen sensors and participate in local autoimmune responses. This study found a correlation between glomerular injury and TLR expression by analysing BXSB/MpJ-Yaa (BXSB-Yaa) lupus model mice. In isolated glomeruli, the mRNA expression of sev...

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Udgivet i:Sci Rep
Main Authors: Kimura, Junpei, Ichii, Osamu, Miyazono, Kosuke, Nakamura, Teppei, Horino, Taro, Otsuka-Kanazawa, Saori, Kon, Yasuhiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252901/
https://ncbi.nlm.nih.gov/pubmed/25468389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07290
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