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An MHC Class II Dependent Activation Loop Between Adipose Tissue Macrophages and CD4(+) T cells Controls Obesity-Induced Inflammation

An adaptive immune response triggered by obesity is characterized by the activation of adipose tissue CD4(+) T cells by unclear mechanisms. We have examined if interactions between adipose tissue macrophages (ATMs) and CD4(+) T cells contribute to adipose tissue metainflammation. Intravital microsco...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Cho, Kae Won, Morris, David L., DelProposto, Jennifer L., Geletka, Lynn, Zamarron, Brian, Martinez-Santibanez, Gabriel, Meyer, Kevin A., Singer, Kanakadurga, O'Rourke, Robert W., Lumeng, Carey N.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252867/
https://ncbi.nlm.nih.gov/pubmed/25310975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.004
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