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Losartan Improves Measures of Activity, Inflammation, and Oxidative Stress in Older Mice

Sarcopenia is an age-related decline in skeletal muscle mass and function that is multifactorial in etiology. Age-related changes in the renin-angiotensin system (RAS), increased oxidative stress, and chronic inflammation likely all contribute to its development. Losartan, an angiotensin II type I r...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Exp Gerontol
Hauptverfasser: Lin, Chung-Hao, Yang, Huanle, Xue, Qian-Li, Chuang, Yi-Fang, Roy, Cindy N., Abadir, Peter, Walston, Jeremy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252828/
https://ncbi.nlm.nih.gov/pubmed/25077714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.07.017
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