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Oxygen free radicals in ischemic acute renal failure in the rat.
During renal ischemia, ATP is degraded to hypoxanthine. When xanthine oxidase converts hypoxanthine to xanthine in the presence of molecular oxygen, superoxide radical (O-2) is generated. We studied the role of O-2 and its reduction product OH X in mediating renal injury after ischemia. Male Sprague...
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| Gepubliceerd in: | J Clin Invest |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
1984
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6434591/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111524 |
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