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Enhanced brain distribution of modified aspartoacylase
Canavan disease is a fatal neurological disorder caused by defects in the gene that produces the enzyme aspartoacylase. Enzyme replacement therapy can potentially be used to overcome these defects if a stable enzyme form can be produced that can gain access to the appropriate neural cells. Achieving...
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| Publicado no: | Mol Genet Metab |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252805/ https://ncbi.nlm.nih.gov/pubmed/25066302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2014.07.002 |
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