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Roles played by acidic lipids in HIV-1 Gag membrane binding
The MA domain mediates plasma membrane (PM) targeting of HIV-1 Gag, leading to particle assembly at the PM. The interaction between MA and acidic phospholipids, in addition to N-terminal myristoyl moiety, promotes Gag binding to lipid membranes. Among acidic phospholipids, PI(4,5)P(2), a PM-specific...
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| Publicado no: | Virus Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252750/ https://ncbi.nlm.nih.gov/pubmed/24998886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.06.015 |
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