Use of monoclonal anti-receptor antibodies to probe the expression of the low density lipoprotein receptor in tissues of normal and Watanabe heritable hyperlipidemic rabbits.

Watanabe Heritable Hyperlipidemic (WHHL) rabbits, like humans with familial hypercholesterolemia, have a genetic defect in the low density lipoprotein (LDL) receptor. WHHL fibroblasts produce a low molecular weight precursor form of the receptor that is not glycosylated normally and is not transport...

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Main Authors: Huettinger, M, Schneider, W J, Ho, Y K, Goldstein, J L, Brown, M S
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC425261/
https://ncbi.nlm.nih.gov/pubmed/6088578
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