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Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation

We consider the inverse and patient specific problem of short term (seconds to minutes) heart rate regulation specified by a system of nonlinear ODEs and corresponding data. We show how a recent method termed the structural correlation method (SCM) can be used for model reduction and for obtaining a...

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Publicat a:Math Biosci
Autors principals: Ottesen, Johnny T., Mehlsen, Jesper, Olufsen, Mette S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252605/
https://ncbi.nlm.nih.gov/pubmed/25050793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2014.07.003
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