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Novel osteoinductive photo-cross-linkable chitosan-lactide-fibrinogen hydrogels enhance bone regeneration in critical size segmental bone defects

The purpose of this study was to develop and characterize a novel photo-cross-linkable chitosan-lactide-fibrinogen (CLF) hydrogel and evaluate the efficacy of bone morphogenetic protein-2 (BMP-2) containing CLF hydrogel for osteogenesis in vitro and in vivo. We synthesized the CLF hydrogels and char...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Kim, Sungwoo, Bedigrew, Katherine, Guda, Teja, Maloney, William J., Park, Sangwon, Wenke, Joseph C., Yang, Yunzhi Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252590/
https://ncbi.nlm.nih.gov/pubmed/25174669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2014.08.028
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