α2-Adrenergic Stimulation of the Ventrolateral Preoptic Nucleus Destabilizes the Anesthetic State

The sleep-promoting ventrolateral preoptic nucleus (VLPO) shares reciprocal inhibitory inputs with wake–active neuronal nuclei, including the locus ceruleus. Electrophysiologically, sleep-promoting neurons in the VLPO are directly depolarized by the general anesthetic isoflurane and hyperpolarized b...

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Publicado en:J Neurosci
Main Authors: McCarren, Hilary S., Chalifoux, Michael R., Han, Bo, Moore, Jason T., Meng, Qing Cheng, Baron-Hionis, Nina, Sedigh-Sarvestani, Madineh, Contreras, Diego, Beck, Sheryl G., Kelz, Max B.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252549/
https://ncbi.nlm.nih.gov/pubmed/25471576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1135-14.2014
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