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Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts.

Purine nucleoside phosphorylase (PNP) deficiency in humans is associated with a severe T cell immunodeficiency. To understand further and exploit this T cell lymphospecificity, we have compared the cytotoxicities and metabolism of deoxyguanosine, the cytotoxic substrate of PNP and of arabinosylguani...

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Bibliografske podrobnosti
Main Authors: Ullman, B, Martin, D W
Format: Artigo
Jezik:Inglês
Izdano: 1984
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC425252/
https://ncbi.nlm.nih.gov/pubmed/6332120
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