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HER2 mediated de novo production of TGFβ leads to SNAIL driven epithelial‐to‐mesenchymal transition and metastasis of breast cancer
HER2 is an important determinant of poor prognosis in breast cancer patients. Studies indicate that HER2 positive tumors are mostly resistant to therapy and have high metastatic potential however, the underlying mechanisms remain unknown. In this study, MDA‐MB‐231 and MCF‐7 breast cancer cells with...
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| Publicado no: | Mol Oncol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252481/ https://ncbi.nlm.nih.gov/pubmed/24994678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.06.006 |
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