Functional domains on von Willebrand factor. Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagen.

We have identified two functional domains on the von Willebrand factor (VWF) moiety of the Factor VIII-von Willebrand factor complex (FVIII-VWF), one interacting with blood platelets, and one interacting with vessel wall collagens, by means of two monoclonal antibodies directed against the VWF molec...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Sixma, J J, Sakariassen, K S, Stel, H V, Houdijk, W P, In der Maur, D W, Hamer, R J, de Groot, P G, van Mourik, J A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425227/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6332119/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111489
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