High-temperature cultivation of recombinant Pichia pastoris increases endoplasmic reticulum stress and decreases production of human interleukin-10

BACKGROUND: The yeast Pichia pastoris (P. pastoris) has become a popular ‘cell factory’ for producing heterologous proteins, but production widely varies among proteins. Cultivation temperature is frequently reported to significantly affect protein production; however, the underlying mechanisms of t...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Microb Cell Fact
Glavni autori: Zhong, Yongjun, Yang, Lu, Guo, Yugang, Fang, Fang, Wang, Dong, Li, Rui, Jiang, Ming, Kang, Wenyao, Ma, Jiajia, Sun, Jie, Xiao, Weihua
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251845/
https://ncbi.nlm.nih.gov/pubmed/25425395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-014-0163-7
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items