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Salinomycin Suppresses PDGFRβ, MYC, and Notch Signaling in Human Medulloblastoma

Medulloblastoma (MB) is the most common childhood brain tumor. Despite improved therapy and management, approximately 30% of patients die of the disease. To search for a more effective therapeutic strategy, the effects of salinomycin were tested on cell proliferation, cell death, and cell cycle prog...

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Detalhes bibliográficos
Publicado no:Austin J Pharmacol Ther
Main Authors: Zhou, Shuang, Wang, Fengfei, Zhang, Ying, Johnson, Max R, Qian, Steven, Wu, Min, Wu, Erxi
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251667/
https://ncbi.nlm.nih.gov/pubmed/25478603
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