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Calcitonin Gene-Related Peptide Regulates Cardiomyocyte Survival through Regulation of Oxidative Stress by PI3K/Akt and MAPK Signaling Pathways

CGRP and specific CGRP receptors are found in the heart where they produce positive-inotropic and anti-apoptotic effects, key adaptations to exercise and cardiovascular disease. PI3K/Akt and MAPK signaling imbalances are associated with cardiomyocyte pathologies; however, the effects of CGRP on thes...

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Detalhes bibliográficos
Publicado no:Ann Clin Exp Hypertens
Main Authors: Umoh, Nsini A., Walker, Robin K., Millis, Richard M., Al-Rubaiee, Mustafa, Gangula, Pandu R., Haddad, Georges E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251564/
https://ncbi.nlm.nih.gov/pubmed/25478604
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