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ACE2 Decreases Formation and Severity of Angiotensin II-induced Abdominal Aortic Aneurysms
OBJECTIVE: Angiotensin converting enzyme 2 (ACE2) cleaves angiotensin II (AngII) to form angiotensin-(1-7) (Ang-(1-7)), which generally opposes effects of AngII. AngII infusion into hypercholesterolemic male mice induces formation of abdominal aortic aneurysms (AAAs). This study tests the hypothesis...
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| 出版年: | Arterioscler Thromb Vasc Biol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250973/ https://ncbi.nlm.nih.gov/pubmed/25301841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304613 |
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