NAT2*6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis

AIM: To investigate an association between N-acetyltransferase 2 (NAT2)-haplotypes/diplotypes and adverse effects in Japanese pulmonary tuberculosis patients. METHODS: We studied 100 patients with pulmonary TB treated with anti-TB drugs including INH. The frequencies and distributions of single nucl...

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Pubblicato in:World J Gastroenterol
Autori principali: Higuchi, Norihide, Tahara, Naoko, Yanagihara, Katsunori, Fukushima, Kiyoyasu, Suyama, Naofumi, Inoue, Yuichi, Miyazaki, Yoshitsugu, Kobayashi, Tsutomu, Yoshiura, Koh-ichiro, Niikawa, Norio, Wen, Chun-Yang, Isomoto, Hajime, Shikuwa, Saburou, Omagari, Katsuhisa, Mizuta, Yohei, Kohno, Shigeru, Tsukamoto, Kazuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2007
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250881/
https://ncbi.nlm.nih.gov/pubmed/18023090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.45.6003
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