Cathepsin B Regulates the Appearance and Severity of Mercury-Induced Inflammation and Autoimmunity

Susceptibility and resistance to systemic autoimmunity are genetically regulated. This is particularly true for murine mercury-induced autoimmunity (mHgIA) where DBA/2J mice are considered resistant to disease including polyclonal B cell activation, autoantibody responses, and immune complex deposit...

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Bibliographic Details
Published in:Toxicol Sci
Main Authors: Toomey, Christopher B., Cauvi, David M., Hamel, John C., Ramirez, Andrea E., Pollard, K. Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Role of Cathepsin B in Mercury-Induced Immune Responses
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250846/
https://ncbi.nlm.nih.gov/pubmed/25237059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu189
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