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Degradation of fibrin and elastin by intact human alveolar macrophages in vitro. Characterization of a plasminogen activator and its role in matrix degradation.

Fibrin deposition is prominent in the histopathology of a number of inflammatory lung diseases. Plasmin, activated locally in the lung, can degrade not only this fibrin but potentially structural proteins important to normal lung architecture. Because alveolar macrophages are prominent in inflammato...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Chapman, H A, Stone, O L, Vavrin, Z
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1984
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425084/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6368589/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111275
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