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1 alpha,25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production of the monokine, mononuclear cell factor.

The monocyte factor, interleukin 1, or other factors homologous with interleukin 1, modulates functions of a variety of cells, including T and B lymphocytes, synovial cells, and chondrocytes. We have reported that a human monocyte cell line, U937, produces interleukin 1 when incubated with a soluble...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Amento, E P, Bhalla, A K, Kurnick, J T, Kradin, R L, Clemens, T L, Holick, S A, Holick, M F, Krane, S M
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1984
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC425075/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6608530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111266
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