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Apoptotic effect of Epigallocatechin-3-gallate on the human gastric cancer cell line MKN45 via activation of the mitochondrial pathway

AIM: To investigate whether Epigallocatechin-3-gallate (EGCG) can induce apoptosis of the gastric cancer cell line MKN45 and its apoptotic pathway. METHODS: To determine this, apoptotic rates of MKN45 cells after EGCG treatment with or without caspase-3 inhibitor were evaluated by Annexin V-FITC + P...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ran, Zhi-Hua, Xu, Qi, Tong, Jin-Lu, Xiao, Shu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250627/
https://ncbi.nlm.nih.gov/pubmed/17696257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i31.4255
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