GnRH Evokes Localized Subplasmalemmal Calcium Signaling in Gonadotropes

The binding of GnRH to its receptor initiates signaling cascades in gonadotropes, which result in enhanced LH and FSH biosynthesis and secretion. This process is necessary for follicular maturation and ovulation. Calcium influx activates MAPKs, which lead to increased transcription of LH and FSH gen...

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Dades bibliogràfiques
Publicat a:Mol Endocrinol
Autors principals: Dang, An K., Murtazina, Dilyara A., Magee, Christianne, Navratil, Amy M., Clay, Colin M., Amberg, Gregory C.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250365/
https://ncbi.nlm.nih.gov/pubmed/25333516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1208
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