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Distinct Behaviour of Sorafenib in Experimental Cachexia-Inducing Tumours: The Role of STAT3

The presence of a tumour is very often associated with wasting in the host, affecting both skeletal muscle and adipose tissue. In the present study we used sorafenib, a multi-kinase inhibitor with anti-tumour activity, in order to investigate the effects of chemotherapy on wasting. Three different e...

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Publicat a:PLoS One
Autors principals: Toledo, Míriam, Penna, Fabio, Busquets, Sílvia, López-Soriano, Francisco J., Argilés, Josep M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250056/
https://ncbi.nlm.nih.gov/pubmed/25436606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113931
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