The Accuracy, Feasibility and Challenges of Sequencing Short Tandem Repeats Using Next-Generation Sequencing Platforms

To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers. Only a handful of previous reports have evaluated the potential of NGS for sequencing short tandem repea...

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Bibliographic Details
Published in:PLoS One
Main Authors: Zavodna, Monika, Bagshaw, Andrew, Brauning, Rudiger, Gemmell, Neil J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250034/
https://ncbi.nlm.nih.gov/pubmed/25436869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113862
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