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Selective vulnerability of the medullary thick ascending limb to anoxia in the isolated perfused rat kidney.

A specific anatomical lesion sharply localized to the cells of the medullary thick ascending limbs (mTAL) and characterized by mitochondrial swelling progressing to nuclear pyknosis and cell death is elicited reproducibly in isolated rat kidneys perfused for 15 or 90 min with cell-free albumin-Ringe...

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Pubblicato in:J Clin Invest
Autori principali: Brezis, M, Rosen, S, Silva, P, Epstein, F H
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1984
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6690477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111189
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