Altered Active Zones, Vesicle Pools, Nerve Terminal Conductivity, and Morphology during Experimental MuSK Myasthenia Gravis

Recent studies demonstrate reduced motor-nerve function during autoimmune muscle-specific tyrosine kinase (MuSK) myasthenia gravis (MG). To further understand the basis of motor-nerve dysfunction during MuSK-MG, we immunized female C57/B6 mice with purified rat MuSK ectodomain. Nerve-muscle preparat...

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Veröffentlicht in:PLoS One
Hauptverfasser: Patel, Vishwendra, Oh, Anne, Voit, Antanina, Sultatos, Lester G., Babu, Gopal J., Wilson, Brenda A., Ho, Mengfei, McArdle, Joseph J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249869/
https://ncbi.nlm.nih.gov/pubmed/25438154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110571
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