Proteogenomic characterization of human colon and rectal cancer

We analyzed proteomes of colon and rectal tumors previously characterized by the Cancer Genome Atlas (TCGA) and performed integrated proteogenomic analyses. Somatic variants displayed reduced protein abundance compared to germline variants. mRNA transcript abundance did not reliably predict protein...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Zhang, Bing, Wang, Jing, Wang, Xiaojing, Zhu, Jing, Liu, Qi, Shi, Zhiao, Chambers, Matthew C., Zimmerman, Lisa J., Shaddox, Kent F., Kim, Sangtae, Davies, Sherri R., Wang, Sean, Wang, Pei, Kinsinger, Christopher R., Rivers, Robert C., Rodriguez, Henry, Townsend, R. Reid, Ellis, Matthew J.C., Carr, Steven A., Tabb, David L., Coffey, Robert J., Slebos, Robbert J.C., Liebler, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249766/
https://ncbi.nlm.nih.gov/pubmed/25043054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13438
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