Proteogenomic characterization of human colon and rectal cancer

We analyzed proteomes of colon and rectal tumors previously characterized by the Cancer Genome Atlas (TCGA) and performed integrated proteogenomic analyses. Somatic variants displayed reduced protein abundance compared to germline variants. mRNA transcript abundance did not reliably predict protein...

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Udgivet i:Nature
Main Authors: Zhang, Bing, Wang, Jing, Wang, Xiaojing, Zhu, Jing, Liu, Qi, Shi, Zhiao, Chambers, Matthew C., Zimmerman, Lisa J., Shaddox, Kent F., Kim, Sangtae, Davies, Sherri R., Wang, Sean, Wang, Pei, Kinsinger, Christopher R., Rivers, Robert C., Rodriguez, Henry, Townsend, R. Reid, Ellis, Matthew J.C., Carr, Steven A., Tabb, David L., Coffey, Robert J., Slebos, Robbert J.C., Liebler, Daniel C.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249766/
https://ncbi.nlm.nih.gov/pubmed/25043054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13438
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