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Phenobarbital Induction and Chemical Synergism Demonstrate the Role of UDP-Glucuronosyltransferases in Detoxification of Naphthalophos by Haemonchus contortus Larvae

We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated with the barbiturate phenobarbital, which is known to induce the activity of a number of detoxification...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Kotze, Andrew C., Ruffell, Angela P., Ingham, Aaron B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249576/
https://ncbi.nlm.nih.gov/pubmed/25288079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03333-14
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