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Effects of Dosage, Comorbidities, and Food on Isoniazid Pharmacokinetics in Peruvian Tuberculosis Patients

Poor response to tuberculosis (TB) therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic (PK) parameters can be affected by several factors, such as comorbidities or the interaction of TB drugs with food. This study aimed to determine the PK of isoniazid...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Requena-Méndez, Ana, Davies, Geraint, Waterhouse, David, Ardrey, Alison, Jave, Oswaldo, López-Romero, Sonia Llanet, Ward, Stephen A., Moore, David A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249529/
https://ncbi.nlm.nih.gov/pubmed/25224007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03258-14
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