Synergistic Combinations of the CCR5 Inhibitor VCH-286 with Other Classes of HIV-1 Inhibitors

Here, we evaluated the in vitro anti-HIV-1 activity of the experimental CCR5 inhibitor VCH-286 as a single agent or in combination with various classes of HIV-1 inhibitors. Although VCH-286 used alone had highly inhibitory activity, paired combinations with different drug classes led to synergistic...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Asin-Milan, Odalis, Sylla, Mohamed, El-Far, Mohamed, Belanger-Jasmin, Geneviève, Haidara, Alpha, Blackburn, Julie, Chamberland, Annie, Tremblay, Cécile L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249518/
https://ncbi.nlm.nih.gov/pubmed/25267674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03630-14
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